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In documented deficiency or specific conditions like uncombable hair syndrome, research has suggested that supplementation may help improve symptoms[9]

In this case, the researchers think that epigenetic markers decrease the availability of the norepinephrine transporter in POTS.[ref] Autoimmune involvement in POTS: Research shows that for some people, POTS can be due to an autoimmune attack on either the adrenergic system or the renin-angiotensin system .[ref][ref] Both systems are important in heart rate and blood flow