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PMID: 36645539

Christen WG, Ajani UA, Glynn RJ, and Hennekens CH (2000)

Although these models are instrumental for mechanistic studies, they fail to fully recapitulate the multifactorial and long-term nature of human ovarian aging, which is shaped by decades of environmental exposures, metabolic comorbidities, genetic heterogeneity, and chronic inflamm-aging settings (Wang et al., 2025