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This is corroborated by the research of Wilkins and Sequoia (396), whose study involving 1,163 children and adults demonstrated that Lactobacillus -based probiotics significantly improved eradication rates when used concomitantly with antibiotics compared to a placebo control

Although promising, the immunogenicity of DNA vaccines is generally lower than that of other platforms when administered in vivo , mainly due to suboptimal cellular uptake and limited plasmid delivery to antigen-presenting cells (APCs) as a result of DNA degradation (Eusbio et al

Immunity 42, 2839

They hypothesized that this prolonged immune response could be due to the prolonged antigen availability by mRNA-LNPs leading to stronger germinal center responses