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Unlike the GPX4 pathway, this pathway affects the levels of peroxyl radicals on the membrane, thereby inhibiting lipid peroxidation (Li et al., 2020), and radiation-induced lipid peroxidation also triggers ferroptosis (Ye et al., 2020)

After purifying 5 l of the PCR products (Thermo Fisher Scientific, Waltham, MA, USA) using enzymatic ExoSAP-ITTM cleanup, 1 l was used for Sanger sequencing

While a mild deficiency might not immediately present noticeable symptoms, untreated cases can lead to: Fatigue, weakness, or persistent feelings of tiredness and lightheadedness

Conclusion and Perspectives This systematic review revealed that microbiome alterations, such as abnormal colonization by C