vitamin b12 injections versus oral supplements vs. Supplements: Which Works Best? B12 Injections vs Pills: Richmond's

However, this study was undertaken in 13 day old mice, as without IR they were not viable, and thus, results are not conclusive [159]

Muscle cramps and weakness If a B12 deficiency is preventing the body from producing enough red blood cells to get oxygen to muscle tissues, you may experience associated symptoms, like sporadic muscle cramps or weakness [3]

Decreased appetite and elimination of food chatter in head

A 12-week randomized trial demonstrated: Average weight loss of 2.6 kg in AOD-9604 group (1 mg/day) versus 0.8 kg in placebo group Preferential reduction in abdominal and visceral fat deposits No adverse effects on carbohydrate metabolism or insulin sensitivity Non-dose-dependent effects, with higher doses (10 mg/day) producing less weight loss than lower doses However, a subsequent 24-week Phase III trial with 502 subjects incorporating intensive diet and exercise showed no statistically significant weight loss compared to placebo, leading to development termination in 2007