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Sleep loss further compromises mitochondrial health by reducing activity in complexes I and IV of the electron transport chain and dysregulating mitochondrial dynamics

Others, such as cytochrome c, are essential for mitochondrial electron transport, and their loss from the mitochondria further contributes to disruption of ATP production and mitochondrial dysfunction

Indeed, PtGSTF1 and PtGSTF2 display a STAV active site motif, PtGSTF3 and 7 a STCT motif and PtGSTF4, 5, and 6 display STAA or STNT motifs (Figure 1)