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doi: 10.1186/s13045-019-0720-y 12 MaLChenCZhaoCLiTMaLJiangJet al

However, their development has been limited by human leukocyte antigen (HLA) restriction and low pMHC presentation levels, resulting in a limited repertoire of well-validated neoantigen peptide-MHC (pMHC) targets 6,7