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Description

Bloodbrain barrier hyperpermeability precedes demyelination in the cuprizone model

Oncotarget 7 , 4084640859 (2016)

In vitro experiments confirmed that SPY1 overexpression significantly activated the GCH1/BH4 signaling pathway in NSC-34 cells transfected with the human SOD1 G93A gene

Integrating computational modeling, multi-omics data, and biomarker-driven stratification within these trials are key to operationalizing precision medicine