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miRNAs are small ncRNA molecules, typically 20-30 nucleotides in length, that serve critical roles in structural, enzymatic and regulatory processes across biological systems (58)

The use of B12 also provides neuroprotective and nerve-regeneration benefits, allowing it to alleviate neuropathic pain and muscular dysfunction by promoting health and muscle recovery

Recent evidence suggests that the autophagy-lysosome pathway is associated with the removal of aggregated polyQ-HTT (Sarkar and Rubinsztein, 2008

EVs derived from different cell types across various species have been shown to cross the BBB both in vitro and in vivo , delivering cargo such as miRNAs, proteins, and drugs to target cells in the brain [37,42]