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Description

Mild and occasional

Testicular tissue contains several selenoproteins including GPx1, GPx3, mGPx4, cGPx4, and GPx5 [4]

Anxiety-like behavior during nicotine withdrawal predict subsequent nicotine consumption in adolescent C57BL/6 mice

The proper functioning of GPX4, a member of the GPX family responsible for converting cytotoxic lipid hydroperoxides (L-OOH) into nontoxic lipid alcohols (L-OH), thus preventing the formation of lethal lipid ROS, is dependent on the indispensable cofactor GSH (45)