glutathione review 2015 Glutathione-Related Enzymes and Proteins: A Best Glutathione Supplement | 4

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However, tumor cells can remodel TME by several means, including increased immunosuppressive population, reduced infiltration of tumor-inhibitory immune cells, reduced presentation of tumor antigens on MHC molecules, and more, allowing them to evade the immune system ( Figure 3F )

These effects directly counteract what the medication is trying to accomplish

(PubMed) Bhatnagar S, Taneja S