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T.MeulenbeltI.SuriP.et al (2013)

On the one hand, TME immunomodulation can trigger macrophage polarization from alternately activated macrophages M2 to classically activated macrophages M1, offering intertumoral H 2 O 2 for the Fenton reaction (Zanganeh et al., 2016), which effectively generates ROS and triggers lipid peroxidation (Yang and Stockwell, 2016

Galactose is an epimer of glucose, which only permits mitochondrial OXPHOS ATP production, due to slower kinetics to utilize galactose in glycolysis 17