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The issue is when that leak gets too wide and things that shouldnt get through doand thats where inflammation and symptoms start showing up. The point here is that your GI symptoms are very real, and they may be a result of intestinal barrier (aka gut lining) damage or dysfunction

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We basically told them what we liked, and they ran with it

TMAO is toxic to the kidney and has been shown to have severe implications in the progression of many diseases such as cardiovascular diseases, heart failure, kidney disease, metabolic syndrome, neurological diseases, and some cancers