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Therefore, it is hypothesized that under laser irradiation, UFCL induces ICD in TNBC by activating ferroptosis, upregulating CRT expression, promoting DC maturation, and enhancing T cell activation and tumor infiltration (Nguyen et al

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The ephrin pathway plays a crucial role in immune function and inflammatory responses and proteomics studies further support evidence of chronic inflammation, perhaps chronic infection (Milivojevic et al., 2020) and immune dysregulation (Giloteaux et al., 2023), with additional links to coagulation abnormalities and chronic infection (Nunes et al., 2022)

Wen CJ, Wu LX, Fu LJ, Shen DY, Zhang X, Zhang YW, Yu J, Zhou HH (2014) Preferential induction of CYP1A1 over CYP1B1 in human breast cancer MCF-7 cells after exposure to berberine