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This age-related decline corresponds with observable decreases in skin elasticity, wound healing capacity, and tissue regeneration

For patients with non-alcoholic fatty liver disease or non-alcoholic steatohepatitis, tirzepatide represents one of the most effective interventions currently available

As seen from the model predictions, the final population PK model provided an adequate description of the geometric mean of the PK data, with the model closely replicating the GH trajectories over time for children and adults with GHD