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Objective physiological data gathered from skin biopsies in this same study showed that after approximately six months of targeted supplementation with L-methylfolate, methylcobalamin, and pyridoxal 5'-phosphate, 73% of the patients demonstrated a measurable increase in calf epidermal nerve fiber density

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Research has shown that false negatives are common when looking at B12 levels alone in blood tests

However, before clicking checkout and starting to supplement your dog, we suggest talking to your trusted veterinarian