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Activation of the nuclear factor-kappa B- (NF-B-) signalling pathway can target genes associated with tumour progression and up-regulate expression of tumour-promoting cytokines and survival genes in tumours (Hsueh et al., 2019)

Abbreviations CLA: Conjugated linoleic acids MDA: Malondialdehyde FBG: Fasting blood glucose c9, t11: Cis9, trans11 t10, c12: Trans 10, cis 12 HbA1c: Glycated hemoglobin A hs-CRP: High sensitivity C-reactive protein NF-B: Nuclear factor kappa B TAC: Total antioxidant capacity TNF-: Tumor necrosis factor- IFN-: Interferon gamma GLUT-4: Glucose transporter 4 PPAR-: Peroxisome proliferator-activated receptor gamma WC: Waist circumference CAT-1: Carnitine-palmitoil-transferase-1 References Peyman N, Rezai-Rad M, Tehrani H, Gholian-Aval M, Vahedian-Shahroodi M, Miri HH

MOTS-C, a mitochondrial-derived peptide, has been investigated for metabolic regulation and exercise performance

diabetes mellitus), or the need is increased due to exercise