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Transmembrane protein 88 (TMEM88) promoter hypomethylation is associated with platinum resistance in ovarian cancer

Likewise, in hSOD1 G93A mouse models of ALS, depletion of GSH resulted in degeneration of spinal motor neurons, dysfunctional mitochondria, and neuron loss 58

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Specifically, studies on glutamine starvation in CRC cells revealed that, with prolonged glutamine starvation, the growth of CRC cells is reduced by approximately 4050% compared with that of CRC cells with sufficient glutamine [10]