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doi: 10.3389/fnins.2019.00654 100 HarrisE

However, although the induction of necroptosis was found to be an effective strategy to kill the glioma cells resistant to apoptosis 45,46 , in our experimental model we did not observe any modulation of RIP1 and RIP3, two molecules that auto- and trans-phosphorylate each other leading to the formation of the necrosome