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doi: 10.1016/j.cmet.2010.11.008

Moreover, a self-adjuvanting gel (SAG) formed by grafting 4-benzimidazole-modified polyethyleneimine (PEI-4BImi) with oxidized dextran which has natural immune-activating properties, can inhibit tumor growth by delivering doxorubicin and the TLR-9 agonist CpG to tumor sites and lymph nodes, promoting antigen presentation and enhancing DC activation within lymph nodes (105)