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486 This dysfunction is driven by ROS, oxidative lipids, endoplasmic reticulum (ER) stress, and genetic predispositions, all of which are worsened by caloric excess

& Kirtikara, K

Golimumab a newer agent with less long-term clinical experience (therefore not used as much to date) a human monoclonal antibody that binds to both the soluble and transmembrane bioactive forms of human TNF

very few hippocampal neurons exceptionally display the morphologic evidence of apoptosis, i.e., dense chromatin condensation called apoptotic bodies (Wyllie et al., 1980)