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In addition, amyloid- tightly interacts with redox-active metals such as copper(II) and iron(II), which catalyze the decomposition of hydrogen peroxide via the Fenton reaction, resulting in the formation of hydroxyl radicals

As we age, the levels of naturally occurring GSH drops, however, in certain disease states the levels drop occurs quicker than normal

At the same time, a significant section of users pushed back against the narrative, arguing that the perceived difference in appearance could easily be explained by lighting variations, harsh sunlight, camera exposure, or post-processing effects

Acknowledgements We thank Professor Michelle Bader in Max Planck Institute for Molecular Genetics (Berlin, Germany) for presenting the TPH1 knockout mice