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2-Aminoadipic acid (2-AAA) (ratio: 0.7), a degradation product of lysine that has not been fully characterized, is a potential modulator of glucose homeostasis in humans

1A) 35,39

In studies that compared TCA monotherapy, gabapentinoid monotherapy, and their combination in patients with neuropathic pain including painful DPN, combination therapy was more effective than monotherapy [84,85]