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Loss of claudin-15, but not claudin-2, causes Na+ deficiency and glucose malabsorption in mouse small intestine

Escape latency was recorded, and the mean of the four starting points was used for data analysis

All 26 of the patients in groups 2, 3, and 4 responded to V-B12 treatment.11 The pattern observed in group 4 showed that the response to V-B12 was a hypertensive (vasoconstrictive) one, in which the MAP initially increased to more than 100 mmHg and then declined to 65 mmHg

This can be given as a one time dose, or following NHS guidelines, can be administered over 3 times a week over 2 weeks, before falling back to a maintenance dose