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Pros: Cons: Evidence Score: 8.8/10 Epithalon is a synthetic tetrapeptide that regulates circadian rhythms by supporting pineal gland function and melatonin production

Its believed to promote musculoskeletal repair by upregulating growth factors, stimulating the formation of new blood vessels, or modulating nitric oxide synthesis, but no mechanism of action has been proven.34 TB4, however, has known mechanisms by which it speeds recovery from injury: inhibiting inflammation, preventing cell death, and (as suspected with BPC) promoting blood vessel formation.35 On top of the benefits for physical recovery, the ability to form new blood vessels points to promising implications for cardiovascular health

Additional etiologies that may mimic Reyes syndrome include viral infections, neuromuscular diseases, adverse drug reactions, and exposure to toxic chemicals and plants that cause hepatocellular damage and encephalopathy

PROTACs: proteolysis-targeted chimeras