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There is a close relationship between autophagy and TMZ resistance since TMZ toxicity depends on both (i) the chaperone protein folding function and (ii) the augmentation of protein degradation pathways, both of which are mediated by the ER and autophagy (Lo Dico et al., 2019)

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While a device like EzeCheck provides a fast, affordable, and reliable hemoglobin estimate for screening highly useful in hospitals and outreach a formal diagnosis for assigning an ICD-10 code (especially for severe or chronic anemia) typically requires confirmation through a full venous blood test analyzed in a laboratory