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10.1523/JNEUROSCI.0964-17.2017 J

Microscopically, the treated animals retained more axons and showed less white matter damage

Conclusion: Overall, this study sheds light on metabolic pathways that are dysregulated in tamoxifen-resistant cell lines and the potential role of each of these pathways in the development of resistance

Cells were incubated in TUNEL reaction mixture (Roche, Germany) at 37 C for one h, washed three times with PBS and incubated in blocking solution for 30 min at room temperature