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Techniques such as fluorescence recovery after photobleaching and dynamic contrast-enhanced magnetic resonance imaging (MRI) have demonstrated that interstitial fluid generally moves at a relatively slow velocity, ranging from 0.1 to 10 m/s, depending on the species under consideration [214]

Corbonnois, L

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When the upstream Wnt signaling pathway is in the activated state, the cytoplasmic tail of LRP5/6 recruits Axin into the complex via phosphorylation by Fzd/Dvl