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Furthermore, compared to other CNS cells like macrophages and astrocytes, microglia maintain lower drug concentrations, exhibit a longer lifespan and a slower division rate, and are capable of extensive brain colonization [11]

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Other symptoms associated with RA include: Fatigue Low-grade fevers Pain and stiffness for longer than 30 minutes in the morning or after sitting Anemia Weight loss RA also has been shown to significantly increase the risk of heart attack and stroke because it can damage the protective sheath around the heart called the pericardium (4)