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While acute interventions like particularly intravenous thrombolysis can improve outcomes if administered quickly after the symptom onset, however, earlier administration of thrombolytic therapy usually failed due to the insufficient of rapid recognition of ischemic stroke, and the time-sensitive thrombolysis is not always accessible (11, 12)

Human sulfide:quinone oxidoreductase catalyzes the first step in hydrogen sulfide metabolism and produces a sulfane sulfur metabolite

Disclosure The authors declared that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

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