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Pathophysiology The pathophysiology of cancer anorexia/cachexia syndrome is complex

10.1038/nature17998 Nature 136 ZhangK.HashimotoK

The primary function of L-Carnitine is to transport long-chain fatty acids into the mitochondria, where they are oxidized and turned into energy

In the present invention, since L-carnitine orotic acid is a substance having a unique physiological activity, it is suitable for the purpose of making an acid addition salt which does not exhibit unwanted toxicity or side effects while maintaining the pharmacological efficacy of L-carnitine