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Here we report the engineering and preclinical development of a bimodal molecule that integrates NMDA receptor antagonism with glucagon-like peptide-1 (GLP-1) receptor agonism to effectively reverse obesity, hyperglycaemia and dyslipidaemia in rodent models of metabolic disease

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Combined research models allow investigation into how NAD+ pathway modulation and mitochondrial redox signalling may intersect in cellular metabolism research