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Signal 22, 346

Additionally, impaired bile flow and altered drug metabolism in hepatic dysfunction can cause drug accumulation in the liver, further elevating the risk of toxicity [86]

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Brain Disord 3(1) Huang HC, Nguyen T, Pickett CB (2002) Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription