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The combination therapy was able to reduce infarct volume, preserve BBB integrity, attenuate microglia activation, decrease the required tPA dose, and improve neurological outcomes, even better than tPA alone [215, 216]

Ongoing research continues to refine these treatments, making them safer and more effective

coli biofilm have been studied, including amikacin (AN), cephalosporins (CE), ceftazidime (CAZ), cefoperazone (CFP), cefepime (FEP), piperacillin (PEF), piperacillin-tazobactam (PTZ), ciprofloxacin (CP), gentamicin (GM), meropenem (MEM), and netilmicin (INN)