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Retrieved May 3, 2025, from [ \- Link Opens in New Tab]( (Notes that riboflavin is a key coenzyme in energy metabolism

We also confirmed the delayed formation of the thiomethyl metabolites compared to conventional APAP metabolites, likely related to delayed reabsorption into the systemic circulation after the enterohepatic circulation

LC reduces pro-oxidant ROS-generating enzymes xanthine-oxidase (XO) and nicotinamide-adenine-dinucleotidephosphate-oxidase (NADPH-oxidase), and chelates metal ions (Fe2 + , Cu +), or acts as a buffer for excessive acetyl groups, that leads to a lower mitochondrial superoxide production [32]