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This advancement as a result of NAC supplementation is accompanied by a moderate increase in granulomatous size and density, as well as augmented phagolysosomal fusion as observed from the microscopic imaging, when compared to the sham-treated controls (Figures 7B,D,E)

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Results indicate that DAMGO and morphine fully inhibit cAMP accumulation, mitragynine and 7-hydroxymitragynine partially inhibit cAMP accumulation, whereas speciofoline has no effect in this assay (Fig

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