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G.GatiC.Han DaoE.RaoY.et al (2018)

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Nevertheless, the Trx system functions as a proficient compensatory antioxidant route that facilitates the advancement of tumors during the later phases of carcinogenesis [8, 9]

In addition to downregulating FASN at the posttranslational level, GSH depletion also decreased the key lipogenic genes at the transcriptional level, most notably Scd1 and Srebf1 (Figure 3, AC)

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