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Many factors can contribute to reduced or cessation of normal thiamine production in adult ruminants, including dietary issues or certain medications

Zinc may promote testosterone production in the testes

also, chemotherapy or radiation therapy Drugs, such as antibiotics, which destroy white blood cells Autoimmune disorders such as sarcoidosis, lupus, rheumatoid arthritis Nutrient deficiencies The causes listed here are commonly associated with this symptom, but low WBCs are not enough to identify the underlying condition responsible

It really seems like a trial and error approach is needed as we are all apparently quite different