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We call a gene that is unable to perform its job a Dirty Gene

J Mol Cell Cardiol 125:185194 Zhong J, Tan Y, Lu J, Liu J, Xiao X, Zhu P et al (2019) Therapeutic contribution of melatonin to the treatment of septic cardiomyopathy: a novel mechanism linking Ripk3-modified mitochondrial performance and Endoplasmic reticulum function