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10.3390/ijms20081821 78 MukaiS.YamasakiK.FujiiM.NagaiT.TeradaN.KataokaH.et al (2020)

showed a 32% drop in chronic low back pain with B12 injections over a two-week period, compared to placebo (it is worth noting that the patients had no form of blood test to assess B12 status)