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The drug resistance may be due to the heterogeneity of liver cancer cells and combination therapy may be a good solution

10.1016/j.neulet.2017.06.052 Neurosci

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BMDL and BMDU of Cd exposure producing 5% and 10% prevalence rates of severe proteinuria Comparing the existing dietary exposure limits for Cd Using the E 2M /E cr 300 g/g creatinine as a toxicity endpoint, JECFA assigned a provisional tolerable weekly intake (PTWI) level for Cd at 7 g per kg body weight per week [4]