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Therefore, future studies should refine the overall network of multiple RCDs in conjunction with multiple regulatory pathways, and explore in depth how these common pathways provide valuable potential therapeutic options for SCI by modulating multiple RCDs to act on the spinal cord in a pro-cellular survival direction and promote damage repair

Losartan, an angiotensin II type 1 receptor antagonist, alleviates mechanical hyperalgesia in a rat model of chemotherapy-induced neuropathic pain by inhibiting inflammatory cytokines in the dorsal root ganglia

With increase in toxin exposure, the demand for glutathione production also rises

Field et al., 2003