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These approaches include hydrophobized low molecular weight poly(acrylic acid) derivatives (amphipols) that successfully stabilized bacteriorhodopsin, the bacterial photosynthetic reaction center, and cytochrome b5, hydrophobically modified natural polymers (amphiphilic carboxymethylpullulans or amphibiopols) that effectively solubilized and stabilized membrane proteins containing either -helix or -sheet domains from the outer membranes of Pseudomonas fluorescens (6), so-called peptitergents composed of amphiphilic alpha helices (7), lipopeptides (8), and poly(ethyleneglycol)-lipid (PEG-lipid) conjugates (9)

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These collective findings prompted us to investigate the mechanism by which GSH is regulated in primary lung epithelial progenitor or LUAD cells and whether PSSG plays a functional role in this regulation

The LKB1AMPK pathway acts as a cell metabolic checkpoint, arresting cell growth under low intracellular ATP conditions, such as in nutrient-deficient states [301]