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63,64 Ultimately, through regulation at the tissue and organ levels, these processes influence the onset and progression of diseases in the organism

Glutathione is generally well-tolerated by most people because it is a substance the body already knows how to process

Cholesterol provides membrane stability and fluidity, is important for the formation of lipid rafts, and is a crucial precursor in the synthesis of steroid hormones, vitamin D and bile acids [44]

To identify which pathway contributes most to QEC tolerance to Cys-Cys limitation, we treated QECs with specific inhibitors targeting STAT3 and NRF2 activity: AG-490 [40] and ML385 [41], respectively