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DOI: 10.1113/jphysiol.1934.sp003147 Gericke A et al (2011): Role of M1, M3, and M5 muscarinic acetylcholine receptors in cholinergic dilation of small arteries studied with gene-targeted mice

Patients in combination therapy group received PEG-IFN-2b for 12 weeks followed by TDF add-on for 36 weeks, TDF monotherapy group received TDF for 48 weeks and control group received follow-up only (Figure 1A)