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To understand the non-monotone behavior of GSH, it is crucial to consider that there are two incoming fluxes to GSH, GS and GR, and two outgoing fluxes, GPX and a large flux out into the blood [Figure 2B]

[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Serviddio G., Bellanti F., Stanca E., Lunetti P., Blonda M., Tamborra R., Siculella L., Vendemiale G., Capobianco L., Giudetti A.M