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Early studies in cats using various administration routes (IV, intra-arterial, intrarenal) and dosages have raised minimal safety concerns, however efficacy results were mixed and follow-up durations were short (23 months)

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How This Study Compares to Other Meta-Analyses Every meta-analysis conducted since 2022 has confirmed the same conclusion: microneedling, alone or in combination with topical treatment, produces significantly better outcomes than topical treatment alone