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Recent advancements in preventing and treating gray hair include topical treatments that stimulate melanin production, antioxidants to combat ROS, and dietary supplements rich in vitamins and minerals

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Preclinical studies demonstrated that AOD-9604 was generally safe after chronic oral application in rats and cynomolgus monkeys, with no genotoxic concerns identified

38,39 Sorafenib and cabozantinib almost completely depleted the pERK signal, while AXT050 and rilotumumab showed inhibition in a range of 882% and 1884%, respectively, across the patients