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The sample size was conditioned by our strict inclusion criteria (i.e., prepubertal children) and further stratification according to the IR status, unlike most previous studies that have relied on heterogeneous populations, without considering the influence of these relevant variability factors

Interestingly the two individuals with active CD and high GPx1 expression had H 2 O 2 -induced cytotoxicity within the healthy control range (i.e., 3.5% and 4.4%)