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31 HSA-SNO binds GSH molecules, releasing nitric oxide (NO), which additionally occupies oxygen binding sites within the mitochondria, thus reducing cellular respiration of cancer cells and indirectly increasing the oxygen concentration needed for PDT

It is a critical process that plays essential roles in organismal development, homeostasis maintenance, and disease pathogenesis ( Aberrent cell death is closely associated with various diseases, and its study holds significant implications for understanding the essence of life processes and for advancing disease treatment, especially in the context of tumors, neurodegenerative diseases, and inflammatory conditions ( Uveitis is a leading cause of vision-threatening ocular inflammation worldwide, characterized by a complex pathogenesis involving immune cell infiltration, oxidative stress, and various forms of cell death ( Table 1 )

Autophagy dismantles worn or damaged components and delivers them to the lysosome, a small acidic compartment that digests waste

But, in 1974 Chicago real estate developer Albert Friedman helped revive the area and coined the name River North for the once-abandoned neighborhood